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Comparative gene identification 58/α/β hydrolase domain 5 lacks lysophosphatidic acid acyltransferase activity

Mutations in the gene encoding comparative gene identification 58 (CGI-58)/α/β hydrolase domain 5 (ABHD5) cause Chanarin-Dorfman syndrome, characterized by excessive triacylglycerol storage in cells and tissues. CGI-58 has been identified as a coactivator of adipose TG lipase (ATGL) and a lysophosph...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: McMahon, Derek, Dinh, Anna, Kurz, Daniel, Shah, Dharika, Han, Gil-Soo, Carman, George M., Brasaemle, Dawn L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4109769/
https://ncbi.nlm.nih.gov/pubmed/24879803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M051151
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