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CGI-58/ABHD5 is phosphorylated on Ser239 by protein kinase A: control of subcellular localization
CGI-58/ABHD5 coactivates adipose triglyceride lipase (ATGL). In adipocytes, CGI-58 binds to perilipin 1A on lipid droplets under basal conditions, preventing interaction with ATGL. Upon activation of protein kinase A (PKA), perilipin 1A is phosphorylated and CGI-58 rapidly disperses into the cytopla...
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| Gepubliceerd in: | J Lipid Res |
|---|---|
| Hoofdauteurs: | , , , , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
The American Society for Biochemistry and Molecular Biology
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4274058/ https://ncbi.nlm.nih.gov/pubmed/25421061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M055004 |
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