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Deficiency of liver Comparative Gene Identification-58 causes steatohepatitis and fibrosis in mice
Triglyceride (TG) accumulation in hepatocytes (hepatic steatosis) preludes the development of advanced nonalcoholic fatty liver diseases (NAFLDs) such as steatohepatitis, fibrosis, and cirrhosis. Mutations in human Comparative Gene Identification-58 (CGI-58) cause cytosolic TG-rich lipid droplets to...
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| Main Authors: | , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3708361/ https://ncbi.nlm.nih.gov/pubmed/23733885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M035519 |
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