PGC1α Expression Defines a Subset of Human Melanoma Tumors with Increased Mitochondrial Capacity and Resistance to Oxidative Stress

Cancer cells reprogram their metabolism using different strategies to meet energy and anabolic demands to maintain growth and survival. Understanding the molecular and genetic determinants of these metabolic programs is critical to successfully exploit them for therapy. Here, we report that the onco...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Vazquez, Francisca, Lim, Ji-Hong, Chim, Helen, Bhalla, Kavita, Girnun, Geoff, Pierce, Kerry, Clish, Clary B., Granter, Scott R., Widlund, Hans R., Spiegelman, Bruce M., Puigserver, Pere
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708305/
https://ncbi.nlm.nih.gov/pubmed/23416000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2012.11.020
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi