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ERRα maintains Mitochondrial Oxidative Metabolism and Constitutes an Actionable Target in PGC1α-elevated Melanomas
The uncontrolled growth of tumors provides metabolic dependencies that can be harnessed for therapeutic benefit. Although tumor cells exhibit these increased metabolic demands due to their rapid proliferation, these metabolic processes are general to all cells, and furthermore, targeted therapeutic...
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| Veröffentlicht in: | Mol Cancer Res |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5954239/ https://ncbi.nlm.nih.gov/pubmed/28596418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-17-0143 |
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