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H3K27me3-mediated PGC1α gene silencing promotes melanoma invasion through WNT5A and YAP
Oncogene-targeted and immune checkpoint therapies have revolutionized the clinical management of malignant melanoma and now offer hope to patients with advanced disease. Intimately connected to patients’ overall clinical risk is whether the initial primary melanoma lesion will metastasize and cause...
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| Publicado no: | J Clin Invest |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6994149/ https://ncbi.nlm.nih.gov/pubmed/31929186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI130038 |
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