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H3K27me3-mediated PGC1α gene silencing promotes melanoma invasion through WNT5A and YAP

Oncogene-targeted and immune checkpoint therapies have revolutionized the clinical management of malignant melanoma and now offer hope to patients with advanced disease. Intimately connected to patients’ overall clinical risk is whether the initial primary melanoma lesion will metastasize and cause...

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Bibliografische gegevens
Gepubliceerd in:J Clin Invest
Hoofdauteurs: Luo, Chi, Balsa, Eduardo, Perry, Elizabeth A., Liang, Jiaxin, Tavares, Clint D., Vazquez, Francisca, Widlund, Hans R., Puigserver, Pere
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994149/
https://ncbi.nlm.nih.gov/pubmed/31929186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI130038
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