microRNA-7 Suppresses the Invasive Potential of Breast Cancer Cells and Sensitizes Cells to DNA Damages by Targeting Histone Methyltransferase SET8

SET8 (SET domain containing 8) is a histone H4 lysine 20 (H4K20)-specific monomethyltransferase in higher eukaryotes that exerts diverse functions in transcription regulation, DNA repair, tumor metastasis, and genome integrity. The activity of SET8 is tightly controlled during cell cycle through pos...

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Détails bibliographiques
Auteurs principaux: Yu, Na, Huangyang, Peiwei, Yang, Xiaohan, Han, Xiao, Yan, Ruorong, Jia, Hongti, Shang, Yongfeng, Sun, Luyang
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2013
Sujets:
Gene Regulation
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3707664/
https://ncbi.nlm.nih.gov/pubmed/23720754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.475657
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