microRNA-7 Suppresses the Invasive Potential of Breast Cancer Cells and Sensitizes Cells to DNA Damages by Targeting Histone Methyltransferase SET8

SET8 (SET domain containing 8) is a histone H4 lysine 20 (H4K20)-specific monomethyltransferase in higher eukaryotes that exerts diverse functions in transcription regulation, DNA repair, tumor metastasis, and genome integrity. The activity of SET8 is tightly controlled during cell cycle through pos...

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Bibliographic Details
Main Authors: Yu, Na, Huangyang, Peiwei, Yang, Xiaohan, Han, Xiao, Yan, Ruorong, Jia, Hongti, Shang, Yongfeng, Sun, Luyang
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2013
Subjects:
Gene Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3707664/
https://ncbi.nlm.nih.gov/pubmed/23720754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.475657
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