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An imprinted rheumatoid arthritis methylome signature reflects pathogenic phenotype
BACKGROUND: A DNA methylation signature has been characterized that distinguishes rheumatoid arthritis (RA) fibroblast like synoviocytes (FLS) from osteoarthritis (OA) FLS. The presence of epigenetic changes in long-term cultured cells suggest that rheumatoid FLS imprinting might contribute to patho...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3706831/ https://ncbi.nlm.nih.gov/pubmed/23631487 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm444 |
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