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Joint-specific DNA methylation and transcriptome signatures in rheumatoid arthritis identify distinct pathogenic processes

Stratifying patients on the basis of molecular signatures could facilitate development of therapeutics that target pathways specific to a particular disease or tissue location. Previous studies suggest that pathogenesis of rheumatoid arthritis (RA) is similar in all affected joints. Here we show tha...

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Bibliografische gegevens
Gepubliceerd in:Nat Commun
Hoofdauteurs: Ai, Rizi, Hammaker, Deepa, Boyle, David L., Morgan, Rachel, Walsh, Alice M., Fan, Shicai, Firestein, Gary S., Wang, Wei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906396/
https://ncbi.nlm.nih.gov/pubmed/27282753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11849
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