Joint-specific DNA methylation and transcriptome signatures in rheumatoid arthritis identify distinct pathogenic processes

Stratifying patients on the basis of molecular signatures could facilitate development of therapeutics that target pathways specific to a particular disease or tissue location. Previous studies suggest that pathogenesis of rheumatoid arthritis (RA) is similar in all affected joints. Here we show tha...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Ai, Rizi, Hammaker, Deepa, Boyle, David L., Morgan, Rachel, Walsh, Alice M., Fan, Shicai, Firestein, Gary S., Wang, Wei
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906396/
https://ncbi.nlm.nih.gov/pubmed/27282753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11849
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