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Joint-specific DNA methylation and transcriptome signatures in rheumatoid arthritis identify distinct pathogenic processes

Stratifying patients on the basis of molecular signatures could facilitate development of therapeutics that target pathways specific to a particular disease or tissue location. Previous studies suggest that pathogenesis of rheumatoid arthritis (RA) is similar in all affected joints. Here we show tha...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Ai, Rizi, Hammaker, Deepa, Boyle, David L., Morgan, Rachel, Walsh, Alice M., Fan, Shicai, Firestein, Gary S., Wang, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906396/
https://ncbi.nlm.nih.gov/pubmed/27282753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11849
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