Joint-specific DNA methylation and transcriptome signatures in rheumatoid arthritis identify distinct pathogenic processes

Stratifying patients on the basis of molecular signatures could facilitate development of therapeutics that target pathways specific to a particular disease or tissue location. Previous studies suggest that pathogenesis of rheumatoid arthritis (RA) is similar in all affected joints. Here we show tha...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Ai, Rizi, Hammaker, Deepa, Boyle, David L., Morgan, Rachel, Walsh, Alice M., Fan, Shicai, Firestein, Gary S., Wang, Wei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4906396/
https://ncbi.nlm.nih.gov/pubmed/27282753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11849
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