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DNA methylome signature in rheumatoid arthritis

OBJECTIVES: Epigenetics can influence disease susceptibility and severity. While DNA methylation of individual genes has been explored in autoimmunity, no unbiased systematic analyses have been reported. Therefore, a genome-wide evaluation of DNA methylation loci in fibroblast-like synoviocytes (FLS...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Nakano, Kazuhisa, Whitaker, John W, Boyle, David L, Wang, Wei, Firestein, Gary S
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549371/
https://ncbi.nlm.nih.gov/pubmed/22736089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2012-201526
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