ロード中...

Mechanistic Basis for Type 2 Long QT Syndrome Caused by KCNH2 Mutations that Disrupt Conserved Arginine Residue in the Voltage Sensor

KCNH2 encodes the Kv11.1 channel, which conducts the rapidly activating delayed rectifier K(+) current (I(Kr)) in the heart. KCNH2 mutations cause type 2 long QT syndrome (LQT2), which increases the risk for life-threatening ventricular arrhythmias. LQT2 mutations are predicted to prolong the cardia...

詳細記述

保存先:
書誌詳細
主要な著者: McBride, Christie M., Smith, Ashley M., Smith, Jennifer L., Reloj, Allison R., Velasco, Ellyn J., Powell, Jonathan, Elayi, Claude S., Bartos, Daniel C., Burgess, Don E., Delisle, Brian P.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3706098/
https://ncbi.nlm.nih.gov/pubmed/23546015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00232-013-9539-6
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!