The Cardiomyocyte Molecular Clock Regulates the Circadian Expression of Kcnh2 and Contributes to Ventricular Repolarization

BACKGROUND: Sudden Cardiac Death (SCD) follows a diurnal variation. Data suggest the timing of SCD is influenced by circadian (~24 hour) changes in neurohumoral and cardiomyocyte-specific regulation of the heart’s electrical properties. OBJECTIVE: The basic helix-loop-helix transcription factors BMA...

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Publicado no:Heart Rhythm
Main Authors: Schroder, Elizabeth A., Burgess, Don E., Zhang, Xiping, Lefta, Mellani, Smith, Jennifer L., Patwardhan, Abhijit, Bartos, Daniel C., Elayi, Claude S., Esser, Karyn A., Delisle, Brian P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4541807/
https://ncbi.nlm.nih.gov/pubmed/25701773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hrthm.2015.02.019
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