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Early and late administration of MnTE-2-PyP(5+) in mitigation and treatment of radiation-induced lung damage

INTRODUCTION: Chronic production of reactive oxygen and nitrogen species is an underlying mechanism of radiation (IR)-induced lung injury. The purpose of this study was to determine the optimum time of an antioxidant and redox-modulating Mn porphyrin, MnTE-2-PyP(5+), delivery to mitigate and/or trea...

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Detalhes bibliográficos
Main Authors: Gauter-Fleckenstein, Benjamin, Fleckenstein, Katharina, Owzar, Kouros, Jiang, Chen, Julio, Reboucas, Batinic-Haberle, Ines, Vujaskovic, Zeljko
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3704177/
https://ncbi.nlm.nih.gov/pubmed/20096348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2010.01.020
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