Robust rat pulmonary radioprotection by a lipophilic Mn N-alkylpyridylporphyrin, MnTnHex-2-PyP(5+)()

With the goal to enhance the distribution of cationic Mn porphyrins within mitochondria, the lipophilic Mn(III)meso-tetrakis(N-n-hexylpyridinium-2-yl)porphyrin, MnTnHex-2-PyP(5+) has been synthesized and tested in several different model of diseases, where it shows remarkable efficacy at as low as 5...

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Detalhes bibliográficos
Main Authors: Gauter-Fleckenstein, Benjamin, Reboucas, Julio S., Fleckenstein, Katharina, Tovmasyan, Artak, Owzar, Kouros, Jiang, Chen, Batinic-Haberle, Ines, Vujaskovic, Zeljko
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949096/
https://ncbi.nlm.nih.gov/pubmed/24624330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2013.12.017
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