Anti-angiogenic action of redox modulating Mn(III) ortho tetrakis N-ethylpyridylporphyrin, MnTE-2-PyP(5+)via suppression of oxidative stress in a mouse model of breast tumor

MnTE-2-PyP(5+) is a potent catalytic scavenger of reactive oxygen and nitrogen species, primarily superoxide and peroxynitrite. It therefore not only attenuates primary oxidative damage, but was found to modulate redox-based signaling pathways (HIF-1α, NF-κB, SP-1 and AP-1), and thus in turn seconda...

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Bibliografiset tiedot
Päätekijät: Rabbani, Zahid N., Spasojevic, Ivan, Zhang, XiuWu, Moeller, Benjamin J., Haberle, Sinisa, Vasquez-Vivar, Jeannette, Dewhirst, Mark W., Vujaskovic, Zeljko, Batinic-Haberle, Ines
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2009
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749298/
https://ncbi.nlm.nih.gov/pubmed/19591920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2009.07.001
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