Mn PORPHYRIN-BASED SOD MIMIC, MnTE-2-PyP(5+), TARGETS MOUSE HEART MITOCHONDRIA

The Mn(III) meso-tetrakis(N-ethylpyridinium-2-yl)porphyrin, Mn(III)TE-2-PyP(5+) (AEOL-10113) has proven effective in treating oxidative stress-induced conditions including cancer, radiation damage, diabetes, and central nervous system trauma. The ortho cationic pyridyl nitrogens of MnTE-2-PyP(5+) ar...

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Autores principales: Spasojevic, Ivan, Chen, Yumin, Noel, Teresa J., Yu, Yiqun, Cole, Marsha P., Zhang, Lichun, Zhao, Yunfeng, St Clair, Daret K., Batinic-Haberle, Ines
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1931511/
https://ncbi.nlm.nih.gov/pubmed/17382200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2007.01.019
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