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The SOD Mimic, MnTE-2-PyP, Protects from Chronic Fibrosis and Inflammation in Irradiated Normal Pelvic Tissues

Pelvic radiation for cancer therapy can damage a variety of normal tissues. In this study, we demonstrate that radiation causes acute changes to pelvic fibroblasts such as the transformation to myofibroblasts and the induction of senescence, which persist months after radiation. The addition of the...

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Podrobná bibliografie
Vydáno v:Antioxidants (Basel)
Hlavní autoři: Shrishrimal, Shashank, Kosmacek, Elizabeth A., Chatterjee, Arpita, Tyson, McDonald J., Oberley-Deegan, Rebecca E.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5745497/
https://ncbi.nlm.nih.gov/pubmed/29113120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox6040087
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