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Fine-Scale Patterns of Population Stratification Confound Rare Variant Association Tests
Advances in next-generation sequencing technology have enabled systematic exploration of the contribution of rare variation to Mendelian and complex diseases. Although it is well known that population stratification can generate spurious associations with common alleles, its impact on rare variant a...
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| Główni autorzy: | , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Public Library of Science
2013
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3701690/ https://ncbi.nlm.nih.gov/pubmed/23861739 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065834 |
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