Increased Frequency and Suppression by Regulatory T Cells in Patients with Acute Myelogenous Leukemia

PURPOSE: Regulatory CD4(+)CD25(high)Foxp3(+) T cells (Treg) control peripheral immune tolerance. Patients with cancer, including those with hematologic malignancies, have elevated numbers of Treg in the peripheral circulation and in tumor tissues. However, mechanisms of suppression and clinical sign...

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Bibliografski detalji
Glavni autori: Szczepanski, Miroslaw J., Szajnik, Marta, Czystowska, Malgorzata, Mandapathil, Magis, Strauss, Laura, Welsh, Ann, Foon, Kenneth A., Whiteside, Theresa L., Boyiadzis, Michael
Format: Artigo
Jezik:Inglês
Izdano: 2009
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700356/
https://ncbi.nlm.nih.gov/pubmed/19417016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-3010
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