Interleukin-15 enhances natural killer cell cytotoxicity in patients with acute myeloid leukemia by upregulating the activating NK cell receptors

Interleukin-15 (IL-15) has a major role in NK-cell homeostasis. Modulation of the relative frequency and expression intensity of the NK-cell receptors by IL-15 may increase NK cell-mediated cytotoxicity in cancer patients. We investigated the receptor repertoire and measured NK-cell activity in newl...

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Hlavní autoři: Szczepanski, Miroslaw J., Szajnik, Marta, Welsh, Ann, Foon, Kenneth A., Whiteside, Theresa L., Boyiadzis, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer-Verlag 2009
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3721322/
https://ncbi.nlm.nih.gov/pubmed/19526239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-009-0724-5
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