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PD-1 Checkpoint Blockade in Acute Myeloid Leukemia
INTRODUCTION: Immune checkpoints are regulatory pathways induced in activated T lymphocytes that regulate antigen responsiveness. These immune checkpoints are hijacked by tumors to promote dysfunction of anti-tumor effector cells and consequently of tumor escape from the host immune system. AREAS CO...
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| Udgivet i: | Expert Opin Biol Ther |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4778424/ https://ncbi.nlm.nih.gov/pubmed/26036819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14712598.2015.1051028 |
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