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PD-1 Checkpoint Blockade in Acute Myeloid Leukemia

INTRODUCTION: Immune checkpoints are regulatory pathways induced in activated T lymphocytes that regulate antigen responsiveness. These immune checkpoints are hijacked by tumors to promote dysfunction of anti-tumor effector cells and consequently of tumor escape from the host immune system. AREAS CO...

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Detalhes bibliográficos
Publicado no:Expert Opin Biol Ther
Main Authors: Sehgal, Alison, Whiteside, Theresa L., Boyiadzis, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4778424/
https://ncbi.nlm.nih.gov/pubmed/26036819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14712598.2015.1051028
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