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PD-1 Checkpoint Blockade in Acute Myeloid Leukemia
INTRODUCTION: Immune checkpoints are regulatory pathways induced in activated T lymphocytes that regulate antigen responsiveness. These immune checkpoints are hijacked by tumors to promote dysfunction of anti-tumor effector cells and consequently of tumor escape from the host immune system. AREAS CO...
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| Publicat a: | Expert Opin Biol Ther |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4778424/ https://ncbi.nlm.nih.gov/pubmed/26036819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14712598.2015.1051028 |
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