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Tumor-Derived Microvesicles Induce, Expand and Up-Regulate Biological Activities of Human Regulatory T Cells (Treg)

BACKGROUND: Tumor-derived microvesicles (TMV) or exosomes are present in body fluids of patients with cancer and might be involved in tumor progression. The frequency and suppressor functions of peripheral blood CD4(+)CD25(high)FOXP3(+) Treg are higher in patients with cancer than normal controls. T...

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Detalhes bibliográficos
Main Authors: Szajnik, Marta, Czystowska, Malgorzata, Szczepanski, Miroslaw J., Mandapathil, Magis, Whiteside, Theresa L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908536/
https://ncbi.nlm.nih.gov/pubmed/20661468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011469
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