Tumor-Derived Microvesicles Promote Regulatory T Cell Expansion and Induce Apoptosis in Tumor-Reactive Activated CD8(+) T Lymphocytes()

Sera of patients with cancer contain membraneous microvesicles (MV) able to induce apoptosis of activated T cells by activating the Fas/Fas ligand pathway. However, the cellular origin of MV found in cancer patients’ sera varies as do their molecular and cellular profiles. To distinguish tumor-deriv...

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Detalhes bibliográficos
Main Authors: Wieckowski, Eva U., Visus, Carmen, Szajnik, Marta, Szczepanski, Miroslaw J., Storkus, Walter J., Whiteside, Theresa L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3721354/
https://ncbi.nlm.nih.gov/pubmed/19692638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900970
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