Tumor-derived microvesicles in sera of patients with head and neck cancer and their role in tumor progression

BACKGROUND: Tumor-derived membranous vesicles (MV) isolated from HNSCC patients' sera induce apoptosis of activated CD8(+) T cells. We tested if MV molecular profile and activity correlate with disease progression. METHODS: CD8(+) Jurkat cells were incubated with MAGE 3/6(+), FasL(+), MHC class...

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Detalhes bibliográficos
Main Authors: Bergmann, Christoph, Strauss, Laura, Wieckowski, Eva, Czystowska, Malgorzata, Albers, Andreas, Wang, Yun, Zeidler, Reinhard, Lang, Stephan, Whiteside, Theresa L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647573/
https://ncbi.nlm.nih.gov/pubmed/19073006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hed.20968
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