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T Regulatory Type 1 Cells in Squamous Cell Carcinoma of the Head and Neck: Mechanisms of Suppression and Expansion in Advanced Disease

PURPOSE: Regulatory T cells play a major role in tumor escape from immunosurveillance. T regulatory cells type 1 (Tr1), a subset of regulatory T cells present in the tumor and peripheral circulation of patients with head and neck squamous cell carcinoma (HNSCC), mediate immune suppression and might...

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Detalhes bibliográficos
Main Authors: Bergmann, Christoph, Strauss, Laura, Wang, Yun, Szczepanski, Miroslaw J., Lang, Stephan, Johnson, Jonas T., Whiteside, Theresa L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708468/
https://ncbi.nlm.nih.gov/pubmed/18559587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-07-5126
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