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Dendritic Cell-Based Autologous Tumor Vaccines for Head and Neck Squamous Cell Carcinoma: Promise vs Reality

BACKGROUND: An autologous vaccine of apoptotic tumor cells (ATC) & dendritic cells (DC) was administered to stage III/IV HNSCC patients to study safety and feasibility. METHODS: Autologous DC were generated from monocytes, loaded with ATC and delivered intranodally. Delayed-type hypersensitivity...

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Detalhes bibliográficos
Publicado no:Head Neck
Main Authors: Whiteside, Theresa L., Ferris, Robert L., Szczepanski, Miroslaw, Tublin, Mitchell, Kiss, Joseph, Johnson, Rita, Johnson, Jonas T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5542585/
https://ncbi.nlm.nih.gov/pubmed/25735641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hed.24025
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