Constitutively Active ALK2 Receptor Mutants Require Type II Receptor Cooperation

Constitutively activating mutations in receptor kinases recruit downstream effector pathways independently of upstream signaling, with consequences ranging from developmental syndromes to cancer. Classic fibrodysplasia ossificans progressiva (FOP) is a congenital syndrome resulting from highly conse...

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Bibliografische gegevens
Hoofdauteurs: Bagarova, Jana, Vonner, Ashley J., Armstrong, Kelli A., Börgermann, Jan, Lai, Carol S. C., Deng, Donna Y., Beppu, Hideyuki, Alfano, Ivan, Filippakopoulos, Panagis, Morrell, Nicholas W., Bullock, Alex N., Knaus, Petra, Mishina, Yuji, Yu, Paul B.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2013
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Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3700091/
https://ncbi.nlm.nih.gov/pubmed/23572558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01595-12
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