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Development of an ALK2-biased BMP type I receptor kinase inhibitor

The bone morphogenetic protein (BMP) signaling pathway has essential functions in development, homeostasis, and in the normal and pathophysiologic remodeling of tissues. Small molecule inhibitors of the BMP receptor kinase family have been useful for probing physiologic functions of BMP signaling in...

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Detalhes bibliográficos
Main Authors: Mohedas, Agustin H., Xing, Xuechao, Armstrong, Kelli A., Bullock, Alex N., Cuny, Gregory D., Yu, Paul B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3901569/
https://ncbi.nlm.nih.gov/pubmed/23547776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb300655w
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