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BMP Type I Receptor ALK2 Is Essential for Proper Patterning at Late Gastrulation During Mouse Embryogenesis

Bone morphogenetic proteins (BMPs) have multiple functions during vertebrate development. Previously, it was shown that BMP type I receptor ALK2 (also known as ACVRI, ActRI, or ActRIA) was important for normal mouse gastrulation by deleting exon 4 or exon 5 of Alk2. Recently, flanking exon 7 by loxP...

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Detalhes bibliográficos
Main Authors: Komatsu, Yoshihiro, Scott, Gregory, Nagy, Andre, Kaartinen, Vesa, Mishina, Yuji
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1780255/
https://ncbi.nlm.nih.gov/pubmed/17117439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.21021
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