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Activin A receptor type 1–mediated BMP signaling regulates RANKL-induced osteoclastogenesis via canonical SMAD-signaling pathway

Bone morphogenetic proteins (BMPs) are important mediators of osteoclast differentiation. Although accumulating evidence has implicated BMPs in osteoblastogenesis, the mechanisms by which BMPs regulate osteoclastogenesis remain unclear. Activin A receptor type 1 (ACVR1) is a BMP type 1 receptor esse...

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Vydáno v:J Biol Chem
Hlavní autoři: Omi, Maiko, Kaartinen, Vesa, Mishina, Yuji
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879329/
https://ncbi.nlm.nih.gov/pubmed/31619522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009521
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