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Bmp2 and Bmp4 Genetically Interact to Support Multiple Aspects of Mouse Development Including Functional Heart Development

Bone morphogenetic proteins (BMPs) have multiple roles during embryogenesis. Current data indicate that the dosage of BMPs is tightly regulated for normal development in mice. Since Bmp2 or Bmp4 homozygous mutant mice show early embryonic lethality, we generated compound heterozygous mice for Bmp2 a...

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Detalhes bibliográficos
Main Authors: Uchimura, Takashi, Komatsu, Yoshihiro, Tanaka, Momo, McCann, Kelly L., Mishina, Yuji
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847484/
https://ncbi.nlm.nih.gov/pubmed/19391114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.20511
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