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BMP2 is Required for Cephalic Neural Tube Closure in the Mouse

BMPs have been shown to play a role in neural tube development particularly as dorsalizing factors. To explore the possibility that BMP2 could play a role in the developing neural tube (NT) beyond the lethality of Bmp2 null embryos we created Bmp2 chimeras from Bmp2 null ES cells and WT blastocysts....

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Detalhes bibliográficos
Main Authors: Castranio, Trisha, Mishina, Yuji
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086576/
https://ncbi.nlm.nih.gov/pubmed/19097048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.21829
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