TLR Accessory Molecule RP105 (CD180) Is Involved in Post-Interventional Vascular Remodeling and Soluble RP105 Modulates Neointima Formation

BACKGROUND: RP105 (CD180) is TLR4 homologue lacking the intracellular TLR4 signaling domain and acts a TLR accessory molecule and physiological inhibitor of TLR4-signaling. The role of RP105 in vascular remodeling, in particular post-interventional remodeling is unknown. METHODS AND RESULTS: TLR4 an...

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Main Authors: Karper, Jacco C., Ewing, Mark M., de Vries, Margreet R., de Jager, Saskia C. A., Peters, Erna A. B., de Boer, Hetty C., van Zonneveld, Anton-Jan, Kuiper, Johan, Huizinga, Eric G., Brondijk, T. Harma C., Jukema, J. Wouter, Quax, Paul H. A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3699456/
https://ncbi.nlm.nih.gov/pubmed/23844130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0067923
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