Deficiency of the TLR4 analogue RP105 aggravates vein graft disease by inducing a pro-inflammatory response

Venous grafts are often used to bypass occlusive atherosclerotic lesions; however, poor patency leads to vein graft disease. Deficiency of TLR4, an inflammatory regulator, reduces vein graft disease. Here, we investigate the effects of the accessory molecule and TLR4 analogue RadioProtective 105 (RP...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Wezel, Anouk, de Vries, Margreet R., Maassen, Johanna M., Kip, Peter, Peters, Erna A., Karper, Jacco C., Kuiper, Johan, Bot, Ilze, Quax, Paul H. A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823661/
https://ncbi.nlm.nih.gov/pubmed/27053419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24248
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