TLR4 Accessory Molecule RP105 (CD180) Regulates Monocyte-Driven Arteriogenesis in a Murine Hind Limb Ischemia Model

AIMS: We investigated the role of the TLR4-accessory molecule RP105 (CD180) in post-ischemic neovascularization, i.e. arteriogenesis and angiogenesis. TLR4-mediated activation of pro-inflammatory Ly6C(hi) monocytes is crucial for effective neovascularization. Immunohistochemical analyses revealed th...

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Hlavní autoři: Bastiaansen, Antonius J. N. M., Karper, Jacco C., Wezel, Anouk, de Boer, Hetty C., Welten, Sabine M. J., de Jong, Rob C. M., Peters, Erna A. B., de Vries, Margreet R., van Oeveren-Rietdijk, Annemarie M., van Zonneveld, Anton Jan, Hamming, Jaap F., Nossent, A. Yaël, Quax, Paul H. A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4063870/
https://ncbi.nlm.nih.gov/pubmed/24945347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0099882
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