Complement factor C5a induces atherosclerotic plaque disruptions

Complement factor C5a and its receptor C5aR are expressed in vulnerable atherosclerotic plaques; however, a causal relation between C5a and plaque rupture has not been established yet. Accelerated atherosclerosis was induced by placing vein grafts in male apoE(−/−) mice. After 24 days, when advanced...

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Bibliographic Details
Published in:J Cell Mol Med
Main Authors: Wezel, Anouk, de Vries, Margreet R, Lagraauw, H Maxime, Foks, Amanda C, Kuiper, Johan, Quax, Paul HA, Bot, Ilze
Format: Artigo
Language:Inglês
Published: BlackWell Publishing Ltd 2014
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244017/
https://ncbi.nlm.nih.gov/pubmed/25124749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12357
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