Lysophosphatidic acid triggers mast cell-driven atherosclerotic plaque destabilization by increasing vascular inflammation

Lysophosphatidic acid (LPA), a bioactive lysophospholipid, accumulates in the atherosclerotic plaque. It has the capacity to activate mast cells, which potentially exacerbates plaque progression. In this study, we thus aimed to investigate whether LPA contributes to plaque destabilization by modulat...

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Main Authors: Bot, Martine, de Jager, Saskia C. A., MacAleese, Luke, Lagraauw, H. Maxime, van Berkel, Theo J. C., Quax, Paul H. A., Kuiper, Johan, Heeren, Ron M. A., Biessen, Erik A. L., Bot, Ilze
格式: Artigo
語言:Inglês
出版: The American Society for Biochemistry and Molecular Biology 2013
主題:
Research Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622323/
https://ncbi.nlm.nih.gov/pubmed/23396975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M032862
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