Lysophosphatidic acid triggers mast cell-driven atherosclerotic plaque destabilization by increasing vascular inflammation

Lysophosphatidic acid (LPA), a bioactive lysophospholipid, accumulates in the atherosclerotic plaque. It has the capacity to activate mast cells, which potentially exacerbates plaque progression. In this study, we thus aimed to investigate whether LPA contributes to plaque destabilization by modulat...

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Main Authors: Bot, Martine, de Jager, Saskia C. A., MacAleese, Luke, Lagraauw, H. Maxime, van Berkel, Theo J. C., Quax, Paul H. A., Kuiper, Johan, Heeren, Ron M. A., Biessen, Erik A. L., Bot, Ilze
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2013
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Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622323/
https://ncbi.nlm.nih.gov/pubmed/23396975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M032862
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