Lysophosphatidic acid triggers mast cell-driven atherosclerotic plaque destabilization by increasing vascular inflammation

Lysophosphatidic acid (LPA), a bioactive lysophospholipid, accumulates in the atherosclerotic plaque. It has the capacity to activate mast cells, which potentially exacerbates plaque progression. In this study, we thus aimed to investigate whether LPA contributes to plaque destabilization by modulat...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Bot, Martine, de Jager, Saskia C. A., MacAleese, Luke, Lagraauw, H. Maxime, van Berkel, Theo J. C., Quax, Paul H. A., Kuiper, Johan, Heeren, Ron M. A., Biessen, Erik A. L., Bot, Ilze
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Biochemistry and Molecular Biology 2013
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3622323/
https://ncbi.nlm.nih.gov/pubmed/23396975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M032862
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