Negative Regulation of TLR4 Signaling by RP105

Activation of Toll-like receptor (TLR) signaling by microbial signatures is critical to the induction of immune responses. Such responses demand tight regulation. RP105 is a TLR homolog, thought to be largely B cell-specific, which lacks a signaling domain. We report that RP105 expression is wide, d...

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Bibliografiske detaljer
Main Authors: Divanovic, Senad, Trompette, Aurelien, Atabani, Sowsan F., Madan, Rajat, Golenbock, Douglas T., Visintin, Alberto, Finberg, Robert W., Tarakhovsky, Alexander, Vogel, Stefanie N., Belkaid, Yasmine, Kurt-Jones, Evelyn A., Karp, Christopher L.
Format: Artigo
Sprog:Inglês
Udgivet: 2005
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2144914/
https://ncbi.nlm.nih.gov/pubmed/15852007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni1198
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