Toll-Like Receptor 4 Agonistic Antibody Promotes Innate Immunity against Severe Pneumonia Induced by Coinfection with Influenza Virus and Streptococcus pneumoniae

Coinfection with bacteria is a major cause of mortality during influenza epidemics. Recently, Toll-like receptor (TLR) agonists were shown to have immunomodulatory functions. In the present study, we investigated the effectiveness and mechanisms of the new TLR4 agonistic monoclonal antibody UT12 aga...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Tanaka, Akitaka, Nakamura, Shigeki, Seki, Masafumi, Fukudome, Kenji, Iwanaga, Naoki, Imamura, Yoshifumi, Miyazaki, Taiga, Izumikawa, Koichi, Kakeya, Hiroshi, Yanagihara, Katsunori, Kohno, Shigeru
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2013
Pynciau:
Clinical Immunology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697446/
https://ncbi.nlm.nih.gov/pubmed/23637040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00010-13
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