Toll-Like Receptor 4 Agonistic Antibody Promotes Innate Immunity against Severe Pneumonia Induced by Coinfection with Influenza Virus and Streptococcus pneumoniae

Coinfection with bacteria is a major cause of mortality during influenza epidemics. Recently, Toll-like receptor (TLR) agonists were shown to have immunomodulatory functions. In the present study, we investigated the effectiveness and mechanisms of the new TLR4 agonistic monoclonal antibody UT12 aga...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Tanaka, Akitaka, Nakamura, Shigeki, Seki, Masafumi, Fukudome, Kenji, Iwanaga, Naoki, Imamura, Yoshifumi, Miyazaki, Taiga, Izumikawa, Koichi, Kakeya, Hiroshi, Yanagihara, Katsunori, Kohno, Shigeru
التنسيق: Artigo
اللغة:Inglês
منشور في: American Society for Microbiology 2013
الموضوعات:
Clinical Immunology
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697446/
https://ncbi.nlm.nih.gov/pubmed/23637040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00010-13
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