Toll-Like Receptor 4 Agonistic Antibody Promotes Host Defense against Chronic Pseudomonas aeruginosa Lung Infection in Mice

Chronic lower respiratory tract infection with Pseudomonas aeruginosa is difficult to treat due to enhanced antibiotic resistance and decreased efficacy of drug delivery to destroyed lung tissue. To determine the potential for restorative immunomodulation therapies, we evaluated the effect of Toll-l...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Nakamura, Shigeki, Iwanaga, Naoki, Seki, Masafumi, Fukudome, Kenji, Oshima, Kazuhiro, Miyazaki, Taiga, Izumikawa, Koichi, Yanagihara, Katsunori, Miyazaki, Yoshitsugu, Mukae, Hiroshi, Kohno, Shigeru
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936359/
https://ncbi.nlm.nih.gov/pubmed/27091927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01384-15
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