Toll-Like Receptor 4 Agonistic Antibody Promotes Host Defense against Chronic Pseudomonas aeruginosa Lung Infection in Mice

Chronic lower respiratory tract infection with Pseudomonas aeruginosa is difficult to treat due to enhanced antibiotic resistance and decreased efficacy of drug delivery to destroyed lung tissue. To determine the potential for restorative immunomodulation therapies, we evaluated the effect of Toll-l...

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Détails bibliographiques
Publié dans:Infect Immun
Auteurs principaux: Nakamura, Shigeki, Iwanaga, Naoki, Seki, Masafumi, Fukudome, Kenji, Oshima, Kazuhiro, Miyazaki, Taiga, Izumikawa, Koichi, Yanagihara, Katsunori, Miyazaki, Yoshitsugu, Mukae, Hiroshi, Kohno, Shigeru
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2016
Sujets:
Microbial Immunity and Vaccines
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936359/
https://ncbi.nlm.nih.gov/pubmed/27091927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01384-15
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