Toll-Like Receptor 4 Agonistic Antibody Promotes Host Defense against Chronic Pseudomonas aeruginosa Lung Infection in Mice

Chronic lower respiratory tract infection with Pseudomonas aeruginosa is difficult to treat due to enhanced antibiotic resistance and decreased efficacy of drug delivery to destroyed lung tissue. To determine the potential for restorative immunomodulation therapies, we evaluated the effect of Toll-l...

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Bibliografske podrobnosti
izdano v:Infect Immun
Main Authors: Nakamura, Shigeki, Iwanaga, Naoki, Seki, Masafumi, Fukudome, Kenji, Oshima, Kazuhiro, Miyazaki, Taiga, Izumikawa, Koichi, Yanagihara, Katsunori, Miyazaki, Yoshitsugu, Mukae, Hiroshi, Kohno, Shigeru
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2016
Teme:
Microbial Immunity and Vaccines
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936359/
https://ncbi.nlm.nih.gov/pubmed/27091927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01384-15
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