In Vitro Activity of Garenoxacin against Streptococcus pneumoniae Mutants with Characterized Resistance Mechanisms

We evaluated the potency of garenoxacin in selecting resistant Streptococcus pneumoniae mutants by determining its mutant prevention concentration, using strains with and without topoisomerase gene mutations, and compared its potency to that of other quinolones. Garenoxacin had a significantly great...

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Detalhes bibliográficos
Main Authors: Yamamoto, Kazuko, Yanagihara, Katsunori, Sugahara, Kazuyuki, Imamura, Yoshifumi, Seki, Masafumi, Izumikawa, Koichi, Kakeya, Hiroshi, Yamamoto, Yoshihiro, Hirakata, Yoichi, Kamihira, Shimeru, Kohno, Shigeru
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Susceptibility
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715604/
https://ncbi.nlm.nih.gov/pubmed/19451290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00176-09
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