In Vitro Activity of Garenoxacin against Streptococcus pneumoniae Mutants with Characterized Resistance Mechanisms

We evaluated the potency of garenoxacin in selecting resistant Streptococcus pneumoniae mutants by determining its mutant prevention concentration, using strains with and without topoisomerase gene mutations, and compared its potency to that of other quinolones. Garenoxacin had a significantly great...

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Autors principals: Yamamoto, Kazuko, Yanagihara, Katsunori, Sugahara, Kazuyuki, Imamura, Yoshifumi, Seki, Masafumi, Izumikawa, Koichi, Kakeya, Hiroshi, Yamamoto, Yoshihiro, Hirakata, Yoichi, Kamihira, Shimeru, Kohno, Shigeru
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2009
Matèries:
Susceptibility
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715604/
https://ncbi.nlm.nih.gov/pubmed/19451290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00176-09
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