Pharmacokinetics of Zanamivir following Intravenous Administration to Subjects with and without Renal Impairment

Intravenous zanamivir is in clinical development for the treatment of influenza in hospitalized patients, many of whom have renal impairment. This open-label study evaluated zanamivir pharmacokinetics and clinical safety following a single 100-mg intravenous infusion dose in subjects with impaired r...

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Bibliographic Details
Main Authors: Weller, Stephen, Jones, Lori S., Lou, Yu, Peppercorn, Amanda, Ng-Cashin, Judith
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
Subjects:
Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697365/
https://ncbi.nlm.nih.gov/pubmed/23587959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02330-12
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