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Population Pharmacokinetic/Pharmacodynamic Analysis of Intravenous Zanamivir in Healthy Adults and Hospitalized Adult and Pediatric Subjects With Influenza

Zanamivir is a potent and highly selective inhibitor of influenza neuraminidase in which the inhibition of this enzyme prevents the virus from infecting other cells and specifically prevents release of the new virion from the host cell membrane. It is available as an oral powder for inhalation and i...

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Podrobná bibliografie
Vydáno v:Clin Transl Sci
Hlavní autoři: Zuo, Peiying, Collins, Jon, Okour, Malek, Barth, Aline, Shortino, Denise, Yates, Phillip, Roberts, Grace, Watson, Helen A., Peppercorn, Amanda, Hossain, Mohammad
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6951463/
https://ncbi.nlm.nih.gov/pubmed/31664778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12697
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