Pharmacokinetics and pharmacodynamics of intravenous artesunate during severe malaria treatment in Ugandan adults

BACKGROUND: Severe malaria is a medical emergency with high mortality. Prompt achievement of therapeutic concentrations of highly effective anti-malarial drugs reduces the risk of death. The aim of this study was to assess the pharmacokinetics and pharmacodynamics of intravenous artesunate in Uganda...

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Detalhes bibliográficos
Main Authors: Byakika-Kibwika, Pauline, Lamorde, Mohammed, Mayito, Jonathan, Nabukeera, Lillian, Mayanja-Kizza, Harriet, Katabira, Elly, Hanpithakpong, Warunee, Obua, Celestino, Pakker, Nadine, Lindegardh, Niklas, Tarning, Joel, de Vries, Peter J, Merry, Concepta
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3489518/
https://ncbi.nlm.nih.gov/pubmed/22540954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-11-132
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